Ozempic Face: Why It Happens and How to Restore Facial Volume

Friday April 25, 2025 | Age Defense, Body Contouring, Botox, Dermal Fillers, Face, Fat Transfer, Lips, Skin Care

Understanding Ozempic Face

Ozempic (semaglutide) and other GLP-1 receptor agonists like Wegovy and Mounjaro have become popular for weight loss. While these medications are effective for shedding pounds, rapid weight loss can lead to an unintended Trusetd Source Checkbox Trusted Source Implications of Ozempic and Other Semaglutide Medications for Facial Plastic Surgeons Facial Plastic Surgery Go to Source consequence : facial volume loss, often called “Ozempic Face.”

When the body loses weight quickly, it sheds fat from all areas—including the face. This loss of facial fat can make the skin appear loose, hollow, or sagging, contributing to an aged or gaunt Trusetd Source Checkbox Trusted Source Journal of Drugs in Dermatology (JDD) Natural Weight Loss or “Ozempic Face”: Demystifying A Social Media Phenomenon Go to Source look . Since facial fat plays a crucial role in maintaining a youthful appearance, individuals experiencing Ozempic Face may seek solutions to restore volume and contour.

Non-Surgical Solutions for Ozempic Face

For those looking to rejuvenate their facial appearance without surgery, several minimally invasive treatments can restore lost volume: heavy woman injecting ozempic into her arm

Dermal Fillers: Hyaluronic acid-based fillers such as Juvéderm and Restylane can add volume to hollowed cheeks, temples, and under-eye areas, providing a lifted and Trusted Source The evolving role of hyaluronic acid fillers for facial volume restoration and contouring: a Canadian overview Clinical, Cosmetic and Investigational Dermatology Go to Source youthful look .
Sculptra®: Unlike traditional fillers, Sculptra stimulates collagen production over time, gradually Trusted Source Poly-L-lactic acid for the aesthetic correction of facial volume loss Aesthetic Surgery Journal Go to Source improving facial volume and skin texture. This option is ideal for individuals seeking a non-surgical alternative to fat grafting and long-lasting, natural results.
Radiesse®: Unlike hyaluronic acid fillers, Radiesse is a calcium hydroxylapatite-based injectable that provides immediate volume restoration while stimulating collagen production for longer-lasting results.

Surgical Options for Long-Lasting Results

For those seeking more permanent solutions, surgical procedures can effectively address significant facial volume loss:

Facial Fat Transfer: This Trusted Source Facial Rejuvenation With Fat Grafting and Fillers Aesthetic Surgery Journal Go to Source technique , also known as fat grafting, provides long-lasting results by using the patient’s own fat to restore volume to the cheeks, temples, and jawline.
Facelift: If significant sagging has occurred, a facelift may be the best option. This procedure lifts and tightens the skin while repositioning fat and tissue for a more Trusted Source Facelift Techniques That Restore Facial Volume Facial Plastic Surgery Go to Source youthful contour.

Conclusion

While Ozempic and similar GLP-1 medications offer impressive weight loss benefits, they can also lead to volume loss in the face. Fortunately, non-surgical and surgical options are available to restore a youthful, refreshed appearance. Consulting with an experienced plastic surgeon can help determine the best approach to achieve natural, long-lasting results.

Sources

¹ Facial Plastic Surgery. Implications of Ozempic and Other Semaglutide Medications for Facial Plastic Surgeons. https://pubmed.ncbi.nlm.nih.gov/37541662/. Accessed February 19, 2025.
² Journal of Drugs in Dermatology (JDD). Natural Weight Loss or “Ozempic Face”: Demystifying A Social Media Phenomenon. https://jddonline.com/articles/natural-weight-loss-or-ozempic-face-demystifying-a-social-media-phenomenon-S1545961624P1367X/. Accessed February 19, 2025.
³ Clinical, Cosmetic and Investigational Dermatology. The evolving role of hyaluronic acid fillers for facial volume restoration and contouring: a Canadian overview. https://pmc.ncbi.nlm.nih.gov/articles/PMC3469309/. Accessed February 19, 2025.
⁴ Aesthetic Surgery Journal. Poly-L-lactic acid for the aesthetic correction of facial volume loss. https://academic.oup.com/asj/article-abstract/25/6/646/189123. Accessed February 19, 2025.
⁵ Aesthetic Surgery Journal. Facial Rejuvenation With Fat Grafting and Fillers. https://pubmed.ncbi.nlm.nih.gov/34002771/. Accessed February 19, 2025.
Facial Plastic Surgery. Facelift Techniques That Restore Facial Volume. https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0036-1592341. Accessed February 19, 2025.
⁶ Facial Plastic Surgery. Facelift Techniques That Restore Facial Volume. https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0036-1592341. Accessed February 19, 2025.